Role of Pilocarpine in Postmortem Interval Estimation

Background: Estimation of time interval since death is an important aspect forensic medicine, it used as evidence in both civil and criminal cases. There are multiple techniques worldwide but reaction pupil to chemical agents currently the topic interest. Studies on role pilocarpine estimating post-mortem (PMI) very limited so current study aimed estimate using eye drops. Methods: An experimental Cross-sectional was conducted at department medicine toxicology a tertiary care hospital Karachi (Autopsy Lab). The diameter each measured Vernier caliper. After that 2% drops were administered eyes. About 10 15 minutes allowed for pupillary reaction. again after 25 minutes. data analyzed Statistical Package Social Science (SPSS) Windows Version 22. p-value ≤ 0.05 considered significant. Results: mean age participants 61 ± 13.4 years reported significant association with postmortem interval. 5 hours 42 3 19 It has been noted longest duration 16 2 strong correlation change Soon death, initial 98.8% while percentage decreases long death. there no administering Conclusion: can be concluded significantly associated response recorded first two up which drop hours. Keywords: Pilocarpine, Postmortem interval, Pupillary